4-Desoxy-4β-(4-methoxycarbonyl-1,2,3-triazol-1-yl)podophyllotoxin dichloromethane solvate
نویسندگان
چکیده
منابع مشابه
4-Desoxy-4β-(4-methoxycarbonyl-1,2,3-triazol-1-yl)podophyllotoxin dichloromethane solvate
In the title compound {systematic name: methyl 1-[12-oxo-10-(3,4,5-trimethoxy-phen-yl)-4,6,13-trioxa-tetra-cyclo-[7.7.0.0(3,7).0(11,15)]hexa-deca-1,3(7),8-trien-16-yl]-1H-1,2,3-triazole-4-carboxyl-ate dichloro-methane solvate}, C(26)H(25)N(3)O(9)·CH(2)Cl(2), the tetra-hydro-furan ring and the six-membered ring fused to it both display envelope conformations.
متن کامل1-{4-[(1H-1,2,4-Triazol-1-yl)methyl]benzyl}-1H-1,2,4-triazol-4-ium perchlorate
In the crystal structure of the title compound, C(12)H(13)N(6) (+)·ClO(4) (-), the cation, located about an inversion center, is monoprotonated, and one H atom is disordered over two sites on N atoms of the two triazole rings, each with an occupancy factor of 0.5. The perchlorate anion has C(2) symmetry, the Cl atom and one O atom lying on the twofold rotation axis; the anion is thus disordered...
متن کامل4-(4-Hydroxymethyl-1H-1,2,3-triazol-1-yl)benzoic acid
In the title compound, C(10)H(9)N(3)O(3), there is a small twist between the benzene and triazole rings [dihedral angle = 6.32 (7)°]; the carb-oxy-lic acid residue is almost coplanar with the benzene ring to which it is attached [O-C-C-C torsion angle = 1.49 (19)°]. The main deviation from coplanarity of the non-H atoms is found for the hy-droxy group which is almost perpendicular to the remain...
متن کامل4-Desoxy-4β-[(5-methoxy-1H-indol-3-yl)oxalylamino]podophyllotoxin methanol solvate
The main mol-ecule of the title solvate, C(33)H(30)N(2)O(10)·CH(3)OH, is a new anti-tumor agent, which shows cytotoxicity against MDR cancer cell lines. It has been synthesized by coupling 4β-amino-podophyllotoxin with (5-meth-oxy-1H-indol-3-yl)glyoxyl chloride and structurally characterized. There are two crystallographically independent mol-ecules in the asymmetric unit, which differ in the d...
متن کامل4-(1,2,4-Triazol-1-yl)aniline
In the title compound, C(8)H(8)N(4), the dihedral angle between the triazole ring [maximum deviation = 0.003 (1) Å] and the benzene ring is 34.57 (7)°. In the crystal, mol-ecules are linked into sheets lying parallel to the ac plane via inter-molecular N-H⋯N and C-H⋯N hydrogen bonds. Aromatic π-π [centroid-centroid distance = 3.6750 (8) Å] stacking and N-H⋯π inter-actions are also observed.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2009
ISSN: 1600-5368
DOI: 10.1107/s1600536809050612